Zampieri P, Aggio S, Roncon L, Rinuncini M, Canova C, Zanazzi G, Fiorencis R, Zonzin P
Department of Cardiology, Ospedale Civile, Rovigo, Italy.
Heart. 1996 Feb;75(2):206-9. doi: 10.1136/hrt.75.2.206.
Five cases of spontaneous coronary artery dissection (SCAD) are reported, three in women and two in men (mean age 44 years; range 28-65), all of whom suffered a myocardial infarction. Common risk factors for coronary artery disease were present in the two men; in the female group one patient was taking an oral contraceptive, one was in the postpartum period, and the third was a smoker. Only the three women received intravenous alteplase and their ejection fraction was normal; both men had impaired left ventricular function. Two patients had SCAD of the left anterior descending coronary artery and three of the right coronary artery. Only the two men had angiographic features of coronary atherosclerotic involvement. No patients required surgical revascularisation or percutaneous transluminal coronary angioplasty. At a mean follow up of 27 months (range 6 to 40) all patients were alive and all but one were asymptomatic.
报告了5例自发性冠状动脉夹层（SCAD）病例，其中3例为女性，2例为男性（平均年龄44岁；范围28 - 65岁），所有患者均发生心肌梗死。两名男性存在常见的冠状动脉疾病危险因素；女性组中，一名患者正在服用口服避孕药，一名处于产后阶段，第三名是吸烟者。只有三名女性接受了静脉注射阿替普酶治疗，且她们的射血分数正常；两名男性的左心室功能均受损。两名患者的左前降支冠状动脉发生SCAD，三名患者的右冠状动脉发生SCAD。只有两名男性具有冠状动脉粥样硬化累及的血管造影特征。没有患者需要进行手术血运重建或经皮冠状动脉腔内血管成形术。平均随访27个月（范围6至40个月）时，所有患者均存活，除一名患者外均无症状。
