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[动物脑组织中鲨烯醇的分离鉴定及其含量测定]

[Isolation and identification of desmosterol and its concentration in animal brain tissue].

作者信息

Palamarchuk V I, Koval' V G

出版信息

Ukr Biokhim Zh. 1977 Mar-Apr;49(2):108-12.

PMID:867530
Abstract

A method is developed for isolating desmosterol fro the brain of some animals. Sterols with Rf 0.37 and 0.51 are identified. Desmosterol is found in the brain unsaponifiable fraction of calves, piggies, chickens and rats. Its content in the mentioned animals brain is compared. Desmosterol content is shown to rise sharply in the rat brain during the first 12 days after birth. Interrelation between the level of sterols in the brain and formation of the nerve tissue myelin sheath is discussed.

摘要

开发了一种从某些动物大脑中分离出胆固醇的方法。鉴定出Rf值为0.37和0.51的甾醇。在小牛、小猪、鸡和大鼠的大脑不皂化物部分中发现了胆固醇。比较了其在上述动物大脑中的含量。结果表明,出生后的前12天,大鼠大脑中的胆固醇含量急剧上升。讨论了大脑中甾醇水平与神经组织髓鞘形成之间的相互关系。

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