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药物性汞中毒性晶状体病变的临床病理研究

A clinical pathologic study of mercurialentis medicamentosus.

作者信息

Garron L K, Wood I S, Spencer W H, Hayes T L

出版信息

Trans Am Ophthalmol Soc. 1976;74:295-320.

PMID:867632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1311519/
Abstract

Thirty-one patients who used eye drops containing the preservative, phenylmercuric nitrate for from 3 to 15 years, developed a brownish pigmentation of the anterior capsule of the pupillary area. Light and electron microscopic studies on two lenses demonstrated deposits of dense particulate material resembling melanin pigment on and in the anterior capsule of the lens in the area of the pupil. Special studies, including electron microprobe analysis and neutron activation analysis established the presence of mercury in a lens with mercurialentis. No mercury was found in two lenses used as controls.

摘要

31名使用含有防腐剂硝酸苯汞的眼药水3至15年的患者,其瞳孔区前囊出现了褐色色素沉着。对两枚晶状体进行的光镜和电镜研究显示,在瞳孔区域晶状体前囊表面及内部有类似黑色素的致密颗粒物质沉积。包括电子微探针分析和中子活化分析在内的特殊研究证实,患有汞性晶状体病的一枚晶状体中存在汞。用作对照的两枚晶状体中未发现汞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/5e0e3c53761d/taos00025-0328-c.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/dfdeacfc13e0/taos00025-0326-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/cdbe15bde3cd/taos00025-0327-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/3717f8c22050/taos00025-0328-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/458114b10aa5/taos00025-0328-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/5e0e3c53761d/taos00025-0328-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/9f1b70bf2e9d/taos00025-0318-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/eaff6496c6ab/taos00025-0320-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/62dfb80e6051/taos00025-0320-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/45c158c641d8/taos00025-0322-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/168cd7361937/taos00025-0323-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/150969f8d9a1/taos00025-0323-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/28ac7fad77fd/taos00025-0324-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/41026f3ae9ce/taos00025-0325-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/dfdeacfc13e0/taos00025-0326-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/cdbe15bde3cd/taos00025-0327-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/3717f8c22050/taos00025-0328-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/458114b10aa5/taos00025-0328-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d3/1311519/5e0e3c53761d/taos00025-0328-c.jpg

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本文引用的文献

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A Colored Reflex from the Anterior Capsule of the Lens Which Occurs in Mercurialism.汞中毒时晶状体前囊出现的一种有色反射。
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