MMWR Morb Mortal Wkly Rep. 1996 Jul 19;45(28):601-3.
Blastomycosis is a disease of humans and animals caused by inhalation of airborne spores from Blastomyces dermatitidis, a dimorphic fungus found in soil. The spectrum of clinical manifestations of blastomycosis includes acute pulmonary disease, subacute and chronic pulmonary disease (most common presentations), and disseminated extrapulmonary disease (cutaneous manifestations are most common, followed by involvement of the bone, the genitourinary tract, and central nervous system). Although the disease is not nationally notifiable, it was designated a reportable condition in Wisconsin in 1984 following two large outbreaks. This report summarizes information about cases of blastomycosis reported in Wisconsin during 1986-1995 and highlights the importance of surveillance for blastomycosis in areas with endemic disease.
芽生菌病是一种人和动物的疾病,由吸入土壤中发现的双相真菌皮炎芽生菌的气传孢子引起。芽生菌病的临床表现谱包括急性肺部疾病、亚急性和慢性肺部疾病(最常见的表现)以及播散性肺外疾病(皮肤表现最常见,其次是骨骼、泌尿生殖道和中枢神经系统受累)。尽管该病并非全国法定报告疾病,但在1984年两次大规模疫情后,威斯康星州将其指定为应报告疾病。本报告总结了1986 - 1995年期间威斯康星州报告的芽生菌病病例信息,并强调了在地方病流行地区对芽生菌病进行监测的重要性。