Izbicki T, Laskowska-Klita T, Liebhart M, Lipińska L
Zakład Onkologii Chirurgicznej Instytutu Matki i Dziecka w Warszawie.
Pediatr Pol. 1995 Nov;70(11):949-53.
The paper presents the review of prognostic factors which were investigated from the first interests of neuroblastoma, as a model for cancer biology in pediatric oncology. The authors on the basis of other authors experiences and on the own observations, as well stress the importance of basic sciences from the field of molecular biology, cytogenetics and biochemistry, leading to better understanding of the nature of neuroblastoma and to introduction of rational treatment. The stratification of neuroblastoma patients according to the known prognostic variables influenced favourably treatment results.
本文对作为儿科肿瘤学中癌症生物学模型的神经母细胞瘤的首批研究关注点——预后因素进行了综述。作者基于其他作者的经验及自身观察，强调了分子生物学、细胞遗传学和生物化学领域基础科学的重要性，这有助于更好地理解神经母细胞瘤的本质并引入合理的治疗方法。根据已知的预后变量对神经母细胞瘤患者进行分层，对治疗结果产生了有利影响。
