Grasland A, Pouchot J, Damade R, Vinceneux P
Service de médecine interne, hôpital Louis-Mourier, Colombes, France.
Rev Med Interne. 1996;17(1):58-60. doi: 10.1016/0248-8663(96)88396-2.
We report the case of an 81 year-old woman admitted because of declining general health, fever and elevated sedimentation rate. Identification of a pelvic mass on the computed tomographic scan led to perform hysterectomy with a working diagnosis of ovarian malignancy. Histological examination revealed typical lesions of polyarteritis nodosa of uterus and fallopian tube vessels. Diffuse process of the vasculitis was suggested by persistence of fever and elevated erythrocyte sedimentation rate after hysterectomy. Treatment consisting of high-dose corticosteroids and pulses of cyclophosphamide resulted in prompt clinical and biological improvement. We discuss the incidence, the clinical features and the localized or diffuse nature of genital involvement in polyarteritis nodosa and other vasculitis.
我们报告了一例81岁女性患者,因全身健康状况下降、发热和血沉升高入院。计算机断层扫描发现盆腔肿块,遂进行子宫切除术,初步诊断为卵巢恶性肿瘤。组织学检查显示子宫和输卵管血管有结节性多动脉炎的典型病变。子宫切除术后持续发热和血沉升高提示血管炎为弥漫性病变。高剂量皮质类固醇和环磷酰胺脉冲治疗使临床和生物学指标迅速改善。我们讨论了结节性多动脉炎和其他血管炎中生殖器受累的发生率、临床特征以及局限性或弥漫性特点。