Robibaro B, Pammer J, Leber J, Knapp S, Vorbach H, Presterl E
Abteilung für Infektionen und Chemotherapie, Universitätsklinik für Innere Medizin I, Wien.
Wien Klin Wochenschr. 1996;108(1):24-7.
Mucormycosis usually occurs in immunocompromised patients or in patients with diabetes mellitus. Pathogens are moulds of the mucorales species. The diagnosis is made by histological examination of biopsies. A 39 year-old patient with insulin-dependent diabetes mellitus was admitted with a tentative diagnosis of a tumour of the maxilla. After diagnosis of hyphae of the mucorales species, the patient's diabetes was stabilised and he was treated over 17 weeks with amphotericin B (40 mg per day) and made a good recovery. A 58 year-old insulin-dependent patient with ethmoidali and sphenoidali sinusitis did not respond to antibiotic therapy. Mucormycosis was diagnosed by means of biopsy. Although treatment with amphotericin B was started, the patient died after 3 weeks due to multiple organ failure.
毛霉菌病通常发生在免疫功能低下的患者或糖尿病患者中。病原体是毛霉目真菌。通过活检组织学检查进行诊断。一名39岁的胰岛素依赖型糖尿病患者因上颌骨肿瘤初步诊断入院。在诊断出毛霉目真菌的菌丝后，患者的糖尿病病情得到稳定，并用两性霉素B（每天40毫克）治疗了17周，恢复良好。一名58岁的胰岛素依赖型筛窦和蝶窦炎患者对抗生素治疗无反应。通过活检诊断为毛霉菌病。尽管开始用两性霉素B治疗，但患者在3周后因多器官衰竭死亡。
