Fruhwirth J, Pascher O, Hauser H, Amann W
Klinische Abteilung für Gefässchirurgie, Universitätsklinik für Chirurgie, Graz.
Wien Klin Wochenschr. 1996;108(7):196-200.
Over a period of 5 years 81 vascular complications after 15,460 catheterizations of the femoral artery for diagnostic (n = 11,883) or therapeutic (n = 3577) procedures were registered. The following complications were observed in declining frequency: 1. False aneurysm (n = 65), 2. arterial occlusion (dissection, embolia, thrombosis) (n = 8), 3. vascular lesion causing profuse bleeding (n = 7), 4. AV-fistula (n = 1). The total complication rate was 0.52%. The complication rate was significantly higher in therapeutical procedures (1,03%) than in diagnostic investigations (0.37%). Pseudoaneurysms were complicated by thrombosis of the femoral vein (n = 3), lymphatic fistula (n = 3) and deep wound infection (n = 9); secondary complication rate 18.5%. Risk factors for local vascular complications are old age, female gender, high grade arteriosclerosis at the puncture site, overweight, manifest arterial hypertension and medication with cumarin, acetylsalicylic acid or heparin. Further complicating factors are connected with technical risks such as duration of the procedure. French size of the catheter, the catheter sheath and multiple punctures. Vascular repair was performed by simple angiography in most cases, but in 14.8% more extensive surgical procedures were required. In patients with signs of occlusive vascular disease the external iliac artery was replaced by a PTFE-vascular access graft in 4 cases and an arterioplasty of the deep femoral artery was performed in 2 patients. 36% of the operations were undertaken as emergencies. Reintervention was necessary for a postoperative bleeding complication in 1 case (surgical complication rate 1.2%). A female patient suffering from aortic valve stenosis died during emergency operation due to massive retroperitoneal hemorrhage after cardiac catheterization (mortality rate 1.2%). Over a median follow-up period of 37 months no late complications of the intervention were recorded, nor recurrences of peripheral arterial occlusive disease.
在5年期间,对15460例因诊断性(n = 11883)或治疗性(n = 3577)操作而进行股动脉插管的患者进行登记,共发生81例血管并发症。观察到的并发症按发生频率递减依次为:1. 假性动脉瘤(n = 65),2. 动脉闭塞(夹层、栓塞、血栓形成)(n = 8),3. 导致大量出血的血管病变(n = 7),4. 动静脉瘘(n = 1)。总并发症发生率为0.52%。治疗性操作的并发症发生率(1.03%)显著高于诊断性检查(0.37%)。假性动脉瘤并发股静脉血栓形成(n = 3)、淋巴瘘(n = 3)和深部伤口感染(n = 9);继发并发症发生率为18.5%。局部血管并发症的危险因素包括老年、女性、穿刺部位的高级别动脉硬化、超重、明显的动脉高血压以及使用香豆素、乙酰水杨酸或肝素进行药物治疗。其他复杂因素与技术风险有关,如操作持续时间、导管的法国规格、导管鞘以及多次穿刺。大多数情况下通过简单的血管造影进行血管修复,但在14.8%的病例中需要更广泛的外科手术。在有闭塞性血管疾病体征的患者中,4例患者的髂外动脉被聚四氟乙烯血管接入移植物替代,2例患者进行了股深动脉成形术。36%的手术是作为急诊进行的。1例患者因术后出血并发症需要再次干预(手术并发症发生率1.2%)。1例患有主动脉瓣狭窄的女性患者在心脏导管插入术后的急诊手术中因大量腹膜后出血死亡(死亡率1.2%)。在中位随访期37个月内,未记录到干预的晚期并发症,也未出现周围动脉闭塞性疾病的复发。