Levy J B, Lachmann R H, Pusey C D
Renal Unit, Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom.
Am J Kidney Dis. 1996 Apr;27(4):573-8. doi: 10.1016/s0272-6386(96)90169-9.
Goodpasture's disease is usually a monophasic illness that can be successfully treated in a large proportion of patients. Recurrent disease is rare. We report a case of Goodpasture's disease in which recurrent pulmonary hemorrhage and glomerulonephritis were observed over 12 years. Antiglomerular basement membrane autoantibody was monitored throughout this period, and we demonstrate the close association of antibody levels with disease recurrence.
肺出血肾炎综合征通常是一种单相疾病，大部分患者可得到成功治疗。疾病复发罕见。我们报告一例肺出血肾炎综合征病例，该患者在12年期间出现复发性肺出血和肾小球肾炎。在此期间持续监测抗肾小球基底膜自身抗体，我们证明了抗体水平与疾病复发密切相关。
