Granowska M, Biassoni L, Carroll M J, Howell R, Mather S J, Ellison D, Granowski A, Britton K E
St. Bartholomew's Hospital and Medical College Imperial Cancer Research Fund, ICRF, Nuclear Medicine Group, London, UK.
Acta Oncol. 1996;35(3):319-21. doi: 10.3109/02841869609101648.
99mTc SM3 radioimmunoscintigraphy is combined with kinetic analysis and probability mapping using a change detection algorithm to investigate axillary node involvement before primary surgery in patients with breast cancer. Whereas planar imaging was unsuccessful, axillary node involvement was correctly determined in 11 out of 13 patients 6 out of 7 true negatives and 5 out of 6 true positives down to 0.35 grams. A prospective study is underway.
99mTc SM3放射免疫闪烁显像结合动力学分析和概率图谱,使用变化检测算法来研究乳腺癌患者在初次手术前腋窝淋巴结受累情况。平面成像未成功,但在13例患者中有11例正确确定了腋窝淋巴结受累情况,7例真阴性中有6例,6例真阳性中有5例,最小可检测至0.35克。一项前瞻性研究正在进行中。