Hanyu H, Shindou H, Sugiki S, Kakizaki D, Abe K, Iwamoto T, Takasaki M, Kasai A
Department of Geriatric Medicine, Tokyo Medical College, Japan.
No To Shinkei. 1996 Apr;48(4):345-9.
MR diffusion-weighted imaging was performed to investigate changes in water diffusion in patients with cerebral infarction, and diffusion-weighted images (DWI) were compared with T2-weighted images (T2WI). Acute and subacute infarcts were seen as areas of high intensity on DWI and showed lower apparent diffusion coefficients (ADCs), while chronic infarcts showed a relative increase in ADCs. The relative ADC increased progressively over time, becoming renormalized at 3 to 4 weeks, and was elevated in the chronic state. On DWI, infarcts as small as 5 to 6 mm in diameter and lesions adjacent to the ventricular or subarachnoid space could be readily identified. DWI was useful for distinguishing acute lesions from chronic lesions in patients with multiple cerebral infarction, and provided valuable pathophysiologic information on the course of ischemic stroke evolution.
进行磁共振扩散加权成像以研究脑梗死患者水扩散的变化，并将扩散加权图像（DWI）与T2加权图像（T2WI）进行比较。急性和亚急性梗死灶在DWI上表现为高强度区域，表观扩散系数（ADC）较低，而慢性梗死灶的ADC相对增加。相对ADC随时间逐渐增加，在3至4周时恢复正常，并在慢性状态下升高。在DWI上，直径小至5至6毫米的梗死灶以及与脑室或蛛网膜下腔相邻的病变很容易被识别。DWI有助于区分多发性脑梗死患者的急性病变和慢性病变，并为缺血性脑卒中的演变过程提供有价值的病理生理信息。
