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对在冠状动脉旁路移植术前取出的闭塞性冠状动脉内帕尔马兹-沙茨支架进行显微镜评估。

Microscopic evaluation of an occluded intracoronary Palmaz-Schatz stent removed before coronary artery bypass grafting.

作者信息

Nixdorff U, Erbel R, Störkel S, Haude M, Oelert H, Kearney P, Meyer J

机构信息

II. Medical Clinic, Johannes Gutenberg-University, Mainz, Germany.

出版信息

Am J Card Imaging. 1995 Oct;9(4):280-4.

PMID:8680146
Abstract

Intracoronary implantation of stent devices is a new interventional technique with a promising role in the treatment of acute coronary occlusions caused by intimal dissection and suboptimal results of percutaneous transluminal coronary angioplasty. However, the prolonged presence of stent material embedded in the arterial wall may generate unknown late consequences. Major complications consist of subacute to chronic occlusion and restenosis. To elucidate the underlying cause we removed an angiographically occluded intracoronary artery Palmaz-Schatz stent before coronary artery bypass grafting. Scanning electron microscopy showed thorough coating of the metal struts of the stent by normal neoendothelial cells. Side branches arising at the level of the stent were patent. According the specific angiographic feature thrombotic occlusion originated distally of the stent.

摘要

冠状动脉内支架装置植入是一种新的介入技术,在治疗由内膜剥离和经皮腔内冠状动脉成形术效果欠佳引起的急性冠状动脉闭塞方面具有广阔前景。然而,嵌入动脉壁的支架材料长期存在可能会产生未知的后期后果。主要并发症包括亚急性至慢性闭塞和再狭窄。为了阐明潜在原因,我们在冠状动脉旁路移植术前取出了血管造影显示闭塞的冠状动脉内帕尔马兹-沙茨支架。扫描电子显微镜显示支架的金属支柱被正常的新生内皮细胞完全覆盖。在支架水平出现的侧支血管通畅。根据特定的血管造影特征,血栓性闭塞起源于支架远端。

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