Borly L, Stage J G, Grønvall S, Højgaard L
Department of Medical Gastroenterology, Hvidovre Hospital, University of Copenhagen, Denmark.
Eur J Gastroenterol Hepatol. 1995 Nov;7(11):1093-7. doi: 10.1097/00042737-199511000-00013.
To investigate gallbladder function by use of cholescintigraphy in patients with acute cholecystitis before and after percutaneous gallbladder drainage.
A cholescintigraphy was performed in 40 patients with acute cholecystitis before and after the performance of percutaneous gallbladder drainage. During the post-drainage cholescintigraphies, a cholecystokinin stimulation was performed to investigate gallbladder emptying in 12 selected patients. Gallbladder pressure and volume were measured before drainage in another group of 12 patients with acute cholecystitis.
As expected, no gallbladder activity was observed in the cholescintigraphies before drainage, except in a patient with an occluding stone in the common bile duct. Cystic duct patency and gallbladder activity were seen in 80% of patients in cholescintigraphies performed after drainage but before any other treatment. Post-drainage cholescintigraphy revealed a mean gallbladder ejection fraction of 24%, which is significantly lower than the corresponding value in normal individuals and gallstone patients without cholecystitis (n = 12). Gallbladder pressure and volume were markedly increased compared with normal values.
The relief of increased gallbladder pressure and volume appears to be important for the re-establishment of gallbladder function.
通过胆囊闪烁显像术研究经皮胆囊引流前后急性胆囊炎患者的胆囊功能。
对40例急性胆囊炎患者在经皮胆囊引流前后进行胆囊闪烁显像术。在引流后的胆囊闪烁显像术中，对12例选定患者进行胆囊收缩素刺激以研究胆囊排空情况。在另一组12例急性胆囊炎患者中，于引流前测量胆囊压力和容积。
正如预期，引流前的胆囊闪烁显像术中未观察到胆囊活动，除了1例胆总管有阻塞性结石的患者。引流后但在进行任何其他治疗前的胆囊闪烁显像术中，80%的患者可见胆囊管通畅和胆囊活动。引流后的胆囊闪烁显像显示平均胆囊排空分数为24%，显著低于正常个体和无胆囊炎的胆结石患者（n = 12）的相应值。与正常值相比，胆囊压力和容积明显增加。
减轻胆囊压力和容积的增加似乎对恢复胆囊功能很重要。
