Naeije R, De Backer D, Vachiéry J L, De Vuyst P
Department of Intensive Care, Erasme University Hospital, Brussels, Belgium.
Chest. 1996 Jul;110(1):286-9. doi: 10.1378/chest.110.1.286.
A 43-year-old woman had two episodes of lung edema at moderate altitudes. She had taken slimming pills containing fenfluramine hydrochloride and diethylpropion hydrochloride. At sea level, catheterization of the right side of the heart showed a mean pulmonary artery pressure of 16 mm Hg, which increased to 34 mm Hg with mild exercise in a supine position. An extensive workup failed to identify a cardiac or a pulmonary cause of pulmonary hypertension. This patient experienced mild primary pulmonary hypertension related to the intake of anorexigens, which was revealed by high-altitude pulmonary edema.
一名43岁女性在中等海拔地区发生了两次肺水肿。她曾服用过含有盐酸芬氟拉明和盐酸二乙丙胺的减肥药。在海平面时,右心导管检查显示平均肺动脉压为16毫米汞柱,仰卧位轻度运动时升至34毫米汞柱。全面检查未能确定肺动脉高压的心脏或肺部病因。该患者经历了与服用食欲抑制剂相关的轻度原发性肺动脉高压,这通过高原肺水肿得以揭示。