Pummerer C, Grässl G, Neu N
Department of Pediatrics, Medical School, University of Innsbruck, Austria.
Eur Heart J. 1995 Dec;16 Suppl O:71-4. doi: 10.1093/eurheartj/16.suppl_o.71.
Cardiac myosin-induced myocarditis proved to be a valuable virus-free murine model with which to investigate autoimmunological mechanisms in inflammatory heart disease. The disease was shown to be T cell-mediated. In this contribution the functional role of CD4 and CD8 molecules and the conditions that are required to make the cardiac tissue susceptible to an autoimmune attack are discussed.
