Kisacik H L, Ozdemir K, Altinyay E, Oğuzhan A, Kural T, Kir M, Kütük E, Göksel S
Department of Cardiology, Ankara Yüksek Ihtisas Hospital, Turkey.
Eur Heart J. 1996 Jan;17(1):113-9. doi: 10.1093/oxfordjournals.eurheartj.a014669.
The object of our study was to compare the value of exercise stress testing with simultaneous dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computed tomography for the diagnosis of coronary artery disease. Sixty-nine patients with either suspected or proven coronary artery disease underwent simultaneous dobutamine technetium-99m isonitrile single-photon emission computed tomography and stress echocardiography, and treadmill exercise electrocardiography. Dobutamine echocardiography and technetium-99m isonitrile single-photon emission computed tomography revealed a higher overall sensitivity than exercise testing (94 vs 60%, P < 0.001), but dobutamine stress echocardiography showed a higher specificity than both technetium-99m isonitrile single-photon emission computed tomography and exercise testing (86 vs 64%, P < 0.05, for both tests). In addition, the diagnostic accuracy of dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computed tomography was higher than that of exercise testing (91 vs 61%, P < 0.001; 86 vs 61%, P < 0.001, respectively). Dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computed tomography are superior to exercise testing in the diagnosis of coronary artery disease, and dobutamine stress echocardiography can act as an alternative to technetium-99m isonitrile single-photon emission computed tomography.
我们研究的目的是比较运动负荷试验联合多巴酚丁胺负荷超声心动图和锝-99m异腈单光子发射计算机断层扫描在诊断冠状动脉疾病方面的价值。69例疑似或确诊为冠状动脉疾病的患者同时接受了多巴酚丁胺锝-99m异腈单光子发射计算机断层扫描、负荷超声心动图检查以及平板运动心电图检查。多巴酚丁胺超声心动图和锝-99m异腈单光子发射计算机断层扫描显示出比运动试验更高的总体敏感性（94%对60%，P<0.001），但多巴酚丁胺负荷超声心动图显示出比锝-99m异腈单光子发射计算机断层扫描和运动试验更高的特异性（86%对64%，两种比较P均<0.05）。此外，多巴酚丁胺负荷超声心动图和锝-99m异腈单光子发射计算机断层扫描的诊断准确性高于运动试验（分别为91%对61%，P<0.001；86%对61%，P<0.001）。多巴酚丁胺负荷超声心动图和锝-99m异腈单光子发射计算机断层扫描在诊断冠状动脉疾病方面优于运动试验，并且多巴酚丁胺负荷超声心动图可作为锝-99m异腈单光子发射计算机断层扫描的替代方法。
