Prvulovich E M, Costa D C, Bomanji J, Clarke G A, Townsend C E, Miller R F, Ell P J
Institute of Nuclear Medicine, University College London Medical School, United Kingdom.
J Nucl Med. 1996 Jun;37(6):995-6.
A 33-yr-old homosexual man with acquired immune deficiency syndrome (AIDS) and Mycobacterium avium intracellulare (MAI) infection presented with fever, sweats, lethargy and dyspnea. A chest radiograph showed cardiomegaly and an echocardiograph revealed a large pericardial effusion. After pericardial aspiration, which confirmed T cell non-Hodgkin's lymphoma, he remained dyspneic. Gallium-67 imaging was performed to determine whether the patient's residual dyspnea was related to pulmonary MAI infection or lymphomatous infiltration of the heart. Planar 67Ga scintigraphy revealed intense tracer uptake in two areas within the mediastinum and surrounding the entire heart shadow but no evidence of pulmonary MAI infection. SPECT 67Ga scintigraphy precisely localized the two mediastinal abnormalities and demonstrated the tracer uptake around the heart to be pericardial rather than myocardial. Gallium-67 scintigraphy suggested that pericardial lymphoma was the likely basis of the patient's dyspnea.
一名33岁的患有获得性免疫缺陷综合征（艾滋病）和鸟分枝杆菌胞内感染（MAI）的同性恋男子，出现发热、盗汗、乏力和呼吸困难症状。胸部X线片显示心脏扩大，超声心动图显示大量心包积液。心包穿刺抽吸确诊为T细胞非霍奇金淋巴瘤后，他仍感呼吸困难。进行了镓-67显像，以确定患者残留的呼吸困难是与肺部MAI感染还是心脏淋巴瘤浸润有关。平面67Ga闪烁显像显示在纵隔内的两个区域以及整个心脏阴影周围有强烈的示踪剂摄取，但没有肺部MAI感染的证据。SPECT 67Ga闪烁显像精确地定位了两个纵隔异常，并显示心脏周围的示踪剂摄取是心包性的而非心肌性的。镓-67闪烁显像提示心包淋巴瘤可能是患者呼吸困难的原因。
