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[柔脑膜肉瘤病的临床表现与诊断]

[Clinical picture and diagnosis of leptomeningeal sarcomatosis].

作者信息

Nesterov L N

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(4):522-7.

PMID:868422
Abstract

The study is based on the analysis of 10 cases of sarcomatosis of the brain and spinal pia mater. A progressive development of the disease, cachaxia, the existence of focal symptoms, radicle pain, xantochromia in the CSF, protein-cell dissociation and some other signs are characteristic of primary sarcomatosis of the pia mater. On the basis of clinical symptoms and CSF changes it is possible vitaly to perform a differential diagnosis with chronic infectious diseases and especially with tubercular meningitis and polyradiculomyelitis. Pathomorphological studies revealed tissue infiltration of the surrounding intracerebral vessels by tumors cells without proliferation into the dura mater and radicles of the spinal cord.

摘要

该研究基于对10例脑和脊髓软脑膜肉瘤病的分析。疾病的进行性发展、恶病质、局灶性症状的存在、神经根痛、脑脊液黄变、蛋白细胞分离及其他一些体征是原发性软脑膜肉瘤病的特征。根据临床症状和脑脊液变化,有可能对慢性传染病,尤其是结核性脑膜炎和多发性神经根脊髓炎进行重要的鉴别诊断。病理形态学研究显示肿瘤细胞浸润脑内周围血管组织,但不累及硬脑膜和脊髓神经根。

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