Rösler J A, Woitowitz H J
Institute and Outpatient Clinic for Occupational and Social Medicine of the Justus, Liebig University, Giessen, Federal Republic of Germany.
Med Lav. 1995 Sep-Oct;86(5):440-8.
The Authors evaluate the risk of lung cancer and mesothelioma among asbestos workers in Germany. 3,988 workers (3,372 male and 616 female) were included in the study, which took into consideration the branch of the asbestos industry in which they had worked, the duration of their employment and also their smoking habits. At the end of the 12 year follow-up, 3,315 workers were alive and 673 dead. The analysis of cause of death showed an increased risk of dying from lung cancer and pleural and peritoneal mesothelioma, in men as well as in women. The risk was shown to be greatest among workers in the asbestos textile industry and among insulators. A probable multiplicative effect of asbestos exposure and smoking on lung cancer causation was noted.
作者评估了德国石棉工人患肺癌和间皮瘤的风险。该研究纳入了3988名工人(3372名男性和616名女性),研究考虑了他们曾工作的石棉行业分支、工作时长以及吸烟习惯。在12年随访结束时,3315名工人存活,673人死亡。死因分析显示,男性和女性死于肺癌、胸膜和腹膜间皮瘤的风险均有所增加。结果表明,石棉纺织行业工人和绝缘材料工人的风险最高。研究还发现石棉暴露和吸烟在导致肺癌方面可能存在相乘效应。