Kiczka K, Kuleszko-Kopystecka H, Bilińska B
Acta Physiol Pol. 1977 Jan-Feb;28(1):1-11.
Effects of strychnine and picrotoxin on the activity of laryngeal and phrenic motoneurons during stimulation of vagus nerve. Acta Physiol. Pol., 1977, 28 (1): 1-11. In paralyzed cats the activity of "single fibres" in the recurrent laryngeal nerve and phrenic nerve was recorded. The afferent part of the vagus nerve was stimulated electrically at a frequency of 200 Hz, the duration of one impulse was 1 msec and voltage values used were 0.1, 0.2 and 0.3 V. Stimulation was carried out in paralyzed animals and then after intravenous administration of strychnine 0.3 mg/kg and picrotoxin 1.0 mg/kg. Administration of the drugs was sufficient to induce in both nerves appearance of additional impulses of varying amplitude. Stimulation after administration of strychnine and picrotoxin caused partial inhibition of the activity of both nerves (less significant than before administration of drugs). The authors believe that the mechanisms of presynaptic and postsynaptic inhibition participate in the activity of nervous pathways conveying the inhibitory effect of the vagus nerve to the laryngeal and phrenic motor neurons.
士的宁和印防己毒素对迷走神经刺激期间喉和膈运动神经元活动的影响。《波兰生理学报》，1977年，28(1):1 - 11。在麻痹的猫中记录了喉返神经和膈神经中“单纤维”的活动。以200 Hz的频率电刺激迷走神经的传入部分，单个脉冲的持续时间为1毫秒，使用的电压值为0.1、0.2和0.3 V。在麻痹动物中进行刺激，然后静脉注射0.3 mg/kg士的宁和1.0 mg/kg印防己毒素后再次刺激。药物给药足以在两条神经中诱发出不同幅度的额外冲动。注射士的宁和印防己毒素后进行刺激导致两条神经的活动部分受到抑制(比给药前的抑制作用小)。作者认为，突触前和突触后抑制机制参与了将迷走神经的抑制作用传递至喉和膈运动神经元的神经通路的活动。
