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宫颈癌放射治疗后的并发症。

Complications after radiation therapy for cervical carcinoma.

作者信息

Bosch A, Frias Z

出版信息

Acta Radiol Ther Phys Biol. 1977 May;16(1):53-62. doi: 10.3109/02841867709133933.

DOI:10.3109/02841867709133933
PMID:868573
Abstract

A series of 1 139 patients with invasive carcinoma of the cervix uteri who received a complete course of treatment by means of external irradiation followed by intracavitary curietherapy was evaluated in order to assess the results of treatment and, in particular, the radiation complications induced. Complications developed in 145 instances (12.7%). Severe complications occurred in only 3 per cent. Twenty-four cases had more than one complication. Rectosigmoidal injuries accounted for 72 per cent of all complications, and appeared earlier than did bladder complications and within the first two years after treatment. No apparent correlation between age and the occurrence of complications was found. The rate was higher in early stages. The radiation complications did not adversely affect the survival results.

摘要

对1139例子宫颈浸润癌患者进行了评估,这些患者接受了外照射后腔内镭疗的完整疗程,以评估治疗结果,特别是所引发的放疗并发症。共出现145例并发症(12.7%)。严重并发症仅占3%。24例患者出现了不止一种并发症。直肠乙状结肠损伤占所有并发症的72%,且比膀胱并发症出现得早,发生在治疗后的头两年内。未发现年龄与并发症发生之间存在明显相关性。早期阶段的发生率较高。放疗并发症并未对生存结果产生不利影响。

相似文献

1
Complications after radiation therapy for cervical carcinoma.宫颈癌放射治疗后的并发症。
Acta Radiol Ther Phys Biol. 1977 May;16(1):53-62. doi: 10.3109/02841867709133933.
2
[Postirradiation proctocolitis].[放射后直肠炎]
God Zb Med Fak Skopje. 1970;16:97-102.
3
High incidence of severe urologic complications following radiotherapy for cervical cancer in Japanese women.日本女性宫颈癌放疗后严重泌尿系统并发症的高发生率。
Gynecol Oncol. 2001 Jan;80(1):21-3. doi: 10.1006/gyno.2000.6030.
4
Bladder and intestinal injuries following intracavitary irradiation of carcinoma of the uterine cervix.
Acta Radiol Ther Phys Biol. 1974 Aug;13(4):288-96. doi: 10.3109/02841867409134482.
5
High external parametrial dose can increase the probability of radiation proctitis in patients with uterine cervix cancer.子宫颈癌患者盆腔外参数剂量过高会增加放射性直肠炎的发生概率。
Gynecol Oncol. 2000 Dec;79(3):406-10. doi: 10.1006/gyno.2000.5997.
6
The correlation of acute toxicity and late rectal injury in radiotherapy for cervical carcinoma: evidence suggestive of consequential late effect (CQLE).宫颈癌放疗中急性毒性与晚期直肠损伤的相关性:提示继发迟发性效应(CQLE)的证据。
Int J Radiat Oncol Biol Phys. 1998 Jan 1;40(1):85-91. doi: 10.1016/s0360-3016(97)00560-9.
7
A simplified method of complete diversionary colostomy for patients with radiation-induced proctosigmoiditis.
Gynecol Oncol. 1977 Jun;5(2):180-6. doi: 10.1016/0090-8258(77)90022-1.
8
[Injuries of the sigmoid colon following radiation therapy of carcinoma of the uterine cervix--a method of estimating the radiation dose to the sigmoid colon].子宫颈癌放射治疗后乙状结肠损伤——一种估计乙状结肠辐射剂量的方法
Nihon Igaku Hoshasen Gakkai Zasshi. 1990 Mar 25;50(3):262-70.
9
Routine clinical estimation of rectal, rectosigmoidal, and bladder doses from intracavitary brachytherapy in the treatment of carcinoma of the cervix.
Int J Radiat Oncol Biol Phys. 1981 May;7(5):653-60. doi: 10.1016/0360-3016(81)90381-3.
10
Early and late radiotherapeutic morbidity in 442 consecutive patients with locally advanced carcinoma of the uterine cervix.442例连续性局部晚期宫颈癌患者的早期和晚期放射治疗并发症
Int J Radiat Oncol Biol Phys. 1994 Jul 30;29(5):941-52. doi: 10.1016/0360-3016(94)90387-5.

引用本文的文献

1
Urological complications after radical hysterectomy with postoperative radiotherapy and radiotherapy alone for cervical cancer.宫颈癌根治性子宫切除术后联合术后放疗及单纯放疗后的泌尿系统并发症。
Medicine (Baltimore). 2018 Mar;97(13):e0173. doi: 10.1097/MD.0000000000010173.
2
[Prevention and therapy of acute radiation-related morbidity of the skin and mucosa. II, Recommendations of the literature].[皮肤和黏膜急性辐射相关发病率的预防与治疗。II,文献推荐]
Strahlenther Onkol. 1998 Apr;174(4):193-9. doi: 10.1007/BF03038526.
3
In vivo rectal inflammatory mediator changes with radiotherapy to the pelvis.
盆腔放疗后体内直肠炎症介质的变化。
Gut. 1993 Sep;34(9):1210-4. doi: 10.1136/gut.34.9.1210.
4
[Surgical problems after radiation therapy (author's transl)].放射治疗后的外科问题(作者译)
Langenbecks Arch Chir. 1981;355:173-9. doi: 10.1007/BF01286836.