Kocián J
I. Interní klinika IPVZ a FTN, Praha.
Vnitr Lek. 1996 Feb;42(2):130-2.
Osteomalacia is a metabolic bone disease caused by deficiency of vitamin D or its active metabolites. Despite a very typical X-ray picture and laboratory finding, it is very poorly diagnosed in the field and thus not treated. This may be due to its atypical clinical picture and also because this disease is frequently omitted in diagnostic considerations. After assessment of the diagnosis the vitamin D treatment or treatment with its metabolites is rapid and successful moreover these substances have also an immunomodulating and anabolic effect.
骨软化症是一种由维生素D或其活性代谢物缺乏引起的代谢性骨病。尽管有非常典型的X线表现和实验室检查结果,但在实际临床中其诊断率很低,因此未得到治疗。这可能是由于其不典型的临床表现,也因为在诊断时常常忽略这种疾病。确诊后,用维生素D或其代谢物进行治疗迅速且有效,此外这些物质还具有免疫调节和合成代谢作用。