Röggla H, Röggla G, Mühlbacher F
Anton-Proksch-Institut, Wien-Kalksburg.
Wien Klin Wochenschr. 1996;108(9):272-5.
Discussion of selection criteria for liver transplantation in alcoholics has been controversial. The concern that there might be a return to alcohol misuse after transplantation which would cause non-compliance with post-transplantation management is not supported by recent reports. Six months of abstinence have been required generally as exclusion criterion, no other psychiatric prognostic factors have been evaluated up to now.
In 39 consecutive patients with alcohol-related end-stage liver disease who were referred to the Surgical University Clinic of Vienna for transplantation the psychiatric prognostic factors abstinence for at least six months, motivation (defined as combination of insight into the necessity of abstinence and readiness for alcohol dependence treatment) and compliance (which was stated to be positive if the psychiatric counselling dates were kept by the patients) were evaluated regarding survival for at least one year.
Abstinence of at least six months failed to prove to be a positive influence on survival. In contrast, motivation and compliance proved to be good psychiatric prognosis parameters.
关于酒精性肝病患者肝移植选择标准的讨论一直存在争议。近期报告并不支持这样一种担忧,即移植后可能会再度滥用酒精,从而导致不遵守移植后管理要求。一般要求戒酒六个月作为排除标准,目前尚未评估其他精神科预后因素。
连续39例酒精性终末期肝病患者被转诊至维也纳大学外科诊所进行移植,评估精神科预后因素,即戒酒至少六个月、动机(定义为对戒酒必要性的认识与接受酒精依赖治疗意愿的结合)以及依从性(如果患者遵守精神科咨询预约时间,则依从性为阳性)对至少存活一年的影响。
戒酒至少六个月并未被证明对存活有积极影响。相比之下,动机和依从性被证明是良好的精神科预后参数。