Office radiotherapy in dermatology: a contemporary perspective.

Ionizing radiation was recognized very early after its discovery as a useful weapon against both neoplasia and inflammation. Following an initial period of enthusiastic use, recognition of its drawbacks and the development of safe and effective alternative treatments for many applications have resulted in a marked reduction in the use of radiotherapy in most dermatological offices. Nonetheless, this modality remains an important component of our modern therapeutic armamentarium. It is a treatment of choice in some situations, and a useful alternative in many more. A thorough understanding of the principles and practice of safe radiotherapy remains vital to the full practice of dermatology in 1996. The present review summarizes the current practice of radiotherapy and offers some guidelines for safe and effective use of this important tool. Detailed discussions of radiobiology, deep radiotherapy (DXRT) and electron beam (EB) therapy are beyond the scope of this clinical review.