Sánchez Muñoz L A, Virosta Allegue M, Franco-Vicario R, Solano López D, Miguel De La Villa F
Servicio de Medicina Interna, Hospital de Basurto-Bilbao.
An Med Interna. 1996 Apr;13(4):181-4.
Relapsing polychondritis is an episodic systemic disorder, characterized by recurrent inflammation that affects cartilaginous structures, the cardiovascular system, eyes and ears. Although the etiology is unknown, experimental evidence strongly suggest that immunologically mediated mechanisms are implicated. Auricular, articular and nasal manifestations are the most frequent disturbances. In about 30% of cases, relapsing polychondritis is associated with other connective tissue diseases and vasculitis. Actually, the diagnosis is based on the criteria proposed by McAdam, and modified by Damiani. We present a case, whose first manifestations of relapsing polychondritis were an intermittent fever and transient arthralgias. Eight months later, auricular chondritis appeared, and gave us the key to diagnosis.
复发性多软骨炎是一种发作性全身性疾病，其特征为反复出现的炎症，累及软骨结构、心血管系统、眼睛和耳朵。尽管病因不明，但实验证据强烈表明免疫介导机制与之相关。耳部、关节和鼻部表现是最常见的病变。约30%的病例中，复发性多软骨炎与其他结缔组织疾病和血管炎相关。实际上，诊断基于麦克亚当提出并经达米亚尼修改的标准。我们报告一例病例，其复发性多软骨炎的首发表现为间歇性发热和短暂关节痛。八个月后，出现了耳软骨炎，为我们提供了诊断线索。
