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感染性椎间盘炎并发细菌性心内膜炎。

Bacterial endocarditis revealed by infectious discitis.

作者信息

Pascaretti C, Legrand E, Laporte J, Fromont P, Masson C, Brégeon C, Audran M

机构信息

Rheumatology Department, Teaching Hospital, Angers, France.

出版信息

Rev Rhum Engl Ed. 1996 Feb;63(2):119-23.

PMID:8689282
Abstract

A study of 30 patients admitted for infectious discitis identified four cases with concomitant bacterial endocarditis. All four patients were male and had concomitant streptococcal septicemia. Two patients had known aortic valve disease. The vertebral infection was located to the thoracic or lumbar spine. Ultrasonography disclosed aortic lesions in all four patients and mitral lesions in two. Management consisted of intravenous antimicrobial therapy for four weeks followed by a three-month course of oral antimicrobial therapy. The outcome of the discitis was favorable within the usual period of time. However, the endocardial lesions continued to progress, and three patients rapidly required valve replacement. Analysis of available data in the 30 patients with discitis showed that half the patients with streptococcal discitis also had bacterial endocarditis and that the latter condition developed in all the patients with streptococcal discitis and a history of valve disease. A number of risk factors were identified. An echocardiogram should be done routinely in patients with infectious discitis and risk factors for bacterial endocarditis.

摘要

一项针对30例因感染性椎间盘炎入院患者的研究发现,有4例同时合并细菌性心内膜炎。所有4例患者均为男性,且同时患有链球菌败血症。2例患者已知患有主动脉瓣疾病。椎体感染位于胸椎或腰椎。超声检查发现所有4例患者均有主动脉病变,2例有二尖瓣病变。治疗包括静脉注射抗菌药物4周,随后进行为期3个月的口服抗菌药物治疗。椎间盘炎的预后在通常时间内良好。然而,心内膜病变持续进展,3例患者很快需要进行瓣膜置换。对30例椎间盘炎患者的现有数据进行分析显示,链球菌性椎间盘炎患者中有一半也患有细菌性心内膜炎,并且在所有有瓣膜疾病病史的链球菌性椎间盘炎患者中均出现了后一种情况。确定了一些危险因素。对于患有感染性椎间盘炎且有细菌性心内膜炎危险因素的患者,应常规进行超声心动图检查。

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