朗格汉斯细胞组织细胞增多症与高钙血症：对吲哚美辛的临床反应
Langerhans cell histiocytosis and hypercalcemia: clinical response to indomethacin.
作者信息
McLean T W, Pritchard J
机构信息
Division of Pediatric Hematology-Oncology, Children's Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115-6084, USA.
出版信息
J Pediatr Hematol Oncol. 1996 Aug;18(3):318-20. doi: 10.1097/00043426-199608000-00019.
PURPOSE
Hypercalcemia is a known complication of childhood malignancies but has never been reported to be associated with Langerhans cell histiocytosis (LCH) in a pediatric patient.
PATIENTS AND METHODS
We describe an infant with multisystem LCH who developed hypercalcemia on two occasions. After being placed on indomethacin, the hypercalcemia did not recur despite disease progression.
CONCLUSION
Hypercalcemia may complicate LCH. If it is demonstrated, indomethacin should be considered as a treatment.
目的
高钙血症是儿童恶性肿瘤已知的并发症，但从未有报道称其与儿科患者的朗格汉斯细胞组织细胞增多症（LCH）相关。
患者与方法
我们描述了一名患有多系统LCH的婴儿，其曾两次出现高钙血症。在使用吲哚美辛后，尽管疾病进展，但高钙血症未再复发。
结论
高钙血症可能使LCH复杂化。如果证实存在高钙血症，应考虑将吲哚美辛作为一种治疗方法。
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