Mete U O, Karaaslan C, Ozbilgin M K, Polat S, Tap O, Kaya M
Department of Histology-Embryology, University of Cukurova, Faculty of Medicine, Adana, Turkey.
Acta Ophthalmol Scand. 1996 Feb;74(1):77-80. doi: 10.1111/j.1600-0420.1996.tb00688.x.
In this study 8 patients with Alport's syndrome are presented. The ocular manifestations of these patients were retinal flecks, macular depigmentation, microspherophakia and anterior lenticonus. One patient revealed bilateral macular hole which was an unusual feature. Four patients had renal biopsies with the characteristic electron microscopic changes of the disease. According to these findings our conclusion is that Alport's syndrome is a disorder of selected basement membranes.
本研究报告了8例Alport综合征患者。这些患者的眼部表现为视网膜斑点、黄斑色素脱失、小球形晶状体和前圆锥形晶状体。1例患者出现双侧黄斑裂孔，这是一个不寻常的特征。4例患者进行了肾活检，发现了该疾病特征性的电子显微镜变化。根据这些发现，我们得出结论，Alport综合征是一种特定基底膜的疾病。
