Sabroe R A, Kennedy C T
Department of Dermatology, Bristol Royal Infirmary, UK.
Clin Exp Dermatol. 1996 Jan;21(1):72-4.
The term orofacial granulomatosis was introduced for orofacial lesions which resemble Crohn's disease clinically and histologically in patients without gastrointestinal disease. The Melkersson-Rosenthal syndrome and its oligosymptomatic form Meischers granulomatous cheilitis are usually felt to be part of the same spectrum of disease. Oedema usually involves tissues of the lower half of the face. We describe a patient with histological changes consistent with those found in orofacial granulomatosis, but with isolated localized oedema of the right periorbital tissues. The patient also had syringomyelia which has not previously been described in association with orofacial granulomatosis.
口面部肉芽肿病这一术语用于描述在无胃肠道疾病的患者中，临床上和组织学上类似于克罗恩病的口面部病变。梅尔克森－罗森塔尔综合征及其症状较少的形式——迈谢尔氏肉芽肿性唇炎，通常被认为是同一疾病谱的一部分。水肿通常累及面部下半部的组织。我们描述了一名患者，其组织学改变与口面部肉芽肿病所见一致，但仅右眶周组织出现局限性水肿。该患者还患有脊髓空洞症，此前尚未见有与口面部肉芽肿病相关的报道。
