非甾体香豆素氨基磺酸盐对雌酮硫酸酯酶的活性位点定向抑制作用。 - Suppr

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超能文献

Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.

作者信息

Woo L W, Purohit A, Reed M J, Potter B V

机构信息

Department of Medicinal Chemistry, School of Pharmacy and Pharmacology, University of Bath, Bath, UK.

出版信息

J Med Chem. 1996 Mar 29;39(7):1349-51. doi: 10.1021/jm950931z.

DOI:10.1021/jm950931z

PMID:8691463

Abstract

摘要

相似文献

Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.非甾体香豆素氨基磺酸盐对雌酮硫酸酯酶的活性位点定向抑制作用。

J Med Chem. 1996 Mar 29;39(7):1349-51. doi: 10.1021/jm950931z.

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Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates.基于三环香豆素的氨基磺酸盐对类固醇硫酸酯酶的强效活性位点定向抑制作用。

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Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES).

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Arch Pharm (Weinheim). 2004 Dec;337(12):634-44. doi: 10.1002/ardp.200400904.

Development of (p-O-sulfamoyl)-N-alkanoyl-phenylalkyl amines as non-steroidal estrone sulfatase inhibitors.（对-氧代-磺酰基）-N-烷酰基-苯烷基胺作为非甾体雌酮硫酸酯酶抑制剂的研发

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In vivo activity of 4-methylcoumarin-7-O-sulfamate, a nonsteroidal, nonestrogenic steroid sulfatase inhibitor.4-甲基香豆素-7-O-氨基磺酸盐的体内活性，一种非甾体、非雌激素类甾体硫酸酯酶抑制剂。

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Synthesis and biological evaluation of fluorinated N-benzoyl and N-phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7-O-sulfamate as steroid sulfatase inhibitors.3-(4-氨基苯基)-香豆素-7-O-氨基磺酸酯的氟化N-苯甲酰基和N-苯基乙酰基衍生物作为类固醇硫酸酯酶抑制剂的合成及生物学评价

Eur J Med Chem. 2017 Mar 10;128:79-87. doi: 10.1016/j.ejmech.2017.01.028. Epub 2017 Jan 22.

Hydrophobicity, a physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES).

Bioorg Med Chem Lett. 2001 Sep 17;11(18):2525-8. doi: 10.1016/s0960-894x(01)00482-6.

引用本文的文献

C-3- and C-4-Substituted Bicyclic Coumarin Sulfamates as Potent Steroid Sulfatase Inhibitors.作为强效类固醇硫酸酯酶抑制剂的C-3和C-4取代双环香豆素氨基磺酸盐

ACS Omega. 2018 Sep 30;3(9):10748-10772. doi: 10.1021/acsomega.8b01383. Epub 2018 Sep 6.

Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds.香豆素：生物活性化合物的天然、有效和多功能支架。

Molecules. 2018 Jan 27;23(2):250. doi: 10.3390/molecules23020250.

Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.用于肿瘤学和女性健康的芳基O-氨基磺酸酯药效团的发现与开发。

J Med Chem. 2015 Oct 8;58(19):7634-58. doi: 10.1021/acs.jmedchem.5b00386. Epub 2015 Jun 12.

A review of coumarin derivatives in pharmacotherapy of breast cancer.香豆素衍生物在乳腺癌药物治疗中的综述。

Curr Med Chem. 2008;15(26):2664-79. doi: 10.2174/092986708786242877.

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