Yano K, Nakano Y, Kobayashi M, Tomita K, Kasamatsu N, Hashizume I
Department of Hematology, Hamamatsu Medical Center, Japan.
Rinsho Ketsueki. 1995 Nov;36(11):1274-8.
A 30-year-female with chronic myelogenous leukemia received allogeneic bone marrow transplantation (BMT). On day 104, low-grade fever, cough, and general malaise developed, resulting in hospitalization 10 days later. Chest X ray revealed diffuse infitrates, suggesting cytomegalovirus interstitial pneumonia. Ganciclovir (DHPG) was given daily and all symptoms disappeared three days later. However, a very few vesicular lesions appeared on her trunk and her two children had chickenpox at that time. Chest CT was taken and disclosed diffuse nodular shadows. Clinical course and chest CT suggested varicella pneumonia. DHPG administration was stopped and acyclovir PO started to be given. She was discharged in excellent condition. In this report, we show a rare case of varicella pneumonia after allogeneic BMT and efficacy of DHPG for the treatment of varicella pneumonia.
一名30岁的慢性粒细胞白血病女性接受了异基因骨髓移植（BMT）。在第104天，出现低热、咳嗽和全身不适，10天后住院。胸部X线显示弥漫性浸润，提示巨细胞病毒间质性肺炎。每天给予更昔洛韦（DHPG），三天后所有症状消失。然而，她的躯干上出现了极少数水疱性病变，当时她的两个孩子患了水痘。进行了胸部CT检查，发现有弥漫性结节阴影。临床病程和胸部CT提示为水痘肺炎。停止使用DHPG，开始口服阿昔洛韦。她出院时状况良好。在本报告中，我们展示了一例异基因BMT后罕见的水痘肺炎病例以及DHPG治疗水痘肺炎的疗效。
