Kapoor V K, Pradeep R, Haribhakti S P, Sikora S S, Kaushik S P
Department of Surgical Gastroenterology, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Lucknow, India.
J Surg Oncol. 1996 Aug;62(4):284-7. doi: 10.1002/(SICI)1096-9098(199608)62:4<284::AID-JSO12>3.0.CO;2-5.
Prognosis of carcinoma of the gallbladder can be improved by diagnosing the disease in the early stages. Records of 14 patients with early (UICC AJCC TNM stages I and II) carcinoma of the gallbladder were analyzed. Clinical presentation in all these patients was like benign biliary disease. Ultrasonography could diagnose carcinoma of the gallbladder in only five patients; in the remaining nine patients, even the ultrasonographic diagnosis was benign biliary disease. All patients were operated; carcinoma of the gallbladder was diagnosed at operation in two more patients, but it was first detected only after histological examination in seven patients. All patients except four had associated gallstones. Preoperative diagnosis of early carcinoma of the gallbladder is difficult. The only way to diagnose early carcinoma of the gallbladder is by early surgical treatment of patients with clinical features of benign biliary disease.
早期诊断胆囊癌可改善其预后。分析了14例早期（国际抗癌联盟美国癌症联合委员会TNM分期I期和II期）胆囊癌患者的记录。所有这些患者的临床表现均类似良性胆道疾病。超声检查仅能诊断出5例胆囊癌；其余9例患者，即使超声检查诊断为良性胆道疾病。所有患者均接受了手术；术中又诊断出2例胆囊癌，但有7例患者是在组织学检查后才首次发现。除4例患者外，所有患者均伴有胆结石。胆囊癌的早期诊断困难。诊断胆囊癌的唯一方法是对具有良性胆道疾病临床特征的患者进行早期手术治疗。
