Niwa H, Masaoka A, Yamakawa Y, Hara F, Kondo K, Fukai I, Kiriyama M, Kondo S
Second Department of Surgery, Nagoya City University, Medical School, Japan.
J Thorac Cardiovasc Surg. 1996 Jul;112(1):124-9. doi: 10.1016/s0022-5223(96)70186-1.
Three infants with congenital tracheal stenosis and three adults with various diseases of the central airway underwent esophageal tracheobronchoplasty to repair long-segment stenoses and defects. The primary operative goal was enlargement of the stenosis (n = 4), repair of the defect (n = 1), or both (n = 1). Cardiopulmonary support was required in two cases. All three infants were operated on for generalized congenital tracheal stenoses. There was one postoperative death on the fifth day. Another infant died of pneumonia 3 months after operation. Tracheal patency was excellent in two infants. One infant is well without symptoms 6 years after the operation, although balloon dilation was required three times during the first postoperative year. In the three adult patients, the primary diseases were congenital tracheal stenosis, iatrogenic injury associated with relapsing polychondritis, and malignant mediastinal tumor involving the trachea. All lesions involved both the trachea and main stem bronchi. Postoperative airway patency was excellent in all three adults, although expandable metallic stents had to be inserted in one patient. Postoperative pulmonary function was improved, particularly forced expiratory volume in 1 second and peak expiratory flow rate. Although the postoperative mortality rate was still high, especially among the infants, and prolonged postoperative ventilatory support was required for five of the six patients, long-term patency and postoperative pulmonary functional improvement are encouraging.
三名患有先天性气管狭窄的婴儿和三名患有各种中央气道疾病的成年人接受了食管气管支气管成形术,以修复长段狭窄和缺损。主要手术目标是扩大狭窄(n = 4)、修复缺损(n = 1)或两者兼顾(n = 1)。两例患者需要心肺支持。所有三名婴儿均因广泛性先天性气管狭窄接受手术。有一例术后第五天死亡。另一例婴儿术后3个月死于肺炎。两名婴儿的气管通畅情况良好。一名婴儿术后6年情况良好且无症状,尽管术后第一年需要进行三次球囊扩张。在三名成年患者中,原发性疾病分别为先天性气管狭窄、与复发性多软骨炎相关的医源性损伤以及累及气管的恶性纵隔肿瘤。所有病变均累及气管和主支气管。所有三名成年患者术后气道通畅情况良好,尽管有一名患者不得不插入可扩张金属支架。术后肺功能有所改善,尤其是第一秒用力呼气量和呼气峰值流速。尽管术后死亡率仍然很高,尤其是在婴儿中,并且六名患者中有五名需要长时间的术后通气支持,但长期通畅和术后肺功能改善令人鼓舞。