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髌腱炎中骨闪烁显像与组织学检查结果的相关性

The correlation of bone scintigraphy and histological findings in patellar tendinitis.

作者信息

Green J S, Morgan B, Lauder I, Finlay D B, Allen M, Belton I

机构信息

Department of Clinical Radiology, Leicester Royal Infirmary NHS Trust, UK.

出版信息

Nucl Med Commun. 1996 Mar;17(3):231-4. doi: 10.1097/00006231-199603000-00010.

Abstract

Patellar tendinitis is a chronic overuse injury causing pain and tenderness over the proximal insertion of the patellar tendon. Its management is usually conservative, but in intractable cases surgery is effective. Bone scintigraphy has been suggested as a useful investigation in these patients, although we are aware of no large series supporting this. Thirty-four patients with intractable symptoms of patellar tendinitis were treated surgically. The operative specimens were graded histologically and compared with preoperative radionuclide bone scans. The histological findings confirmed tendon and or tendon sheath abnormalities in all the samples. The predominant abnormalities were increased vascularity, fibroblast proliferation, acid mucopolysaccharide and haemosiderin deposition. Bone scintigraphy showed 24 (71%) patients to have abnormalities on the delayed images, 8 with diffusely increased activity in the patella and 16 with increased activity localized to the lower pole. Patients with abnormal bone scans had significantly more severe histological changes in their tendons. These findings support the use of radionuclide bone scans in the pre-operative assessment of patellar tendinitis correlating well with histopathological severity of the disease process. The 10 false-negative cases (29%), however, suggest that bone scans are unhelpful in the routine diagnosis and management of this condition.

摘要

髌腱炎是一种慢性过度使用性损伤,导致髌腱近端附着处疼痛和压痛。其治疗通常是保守的,但在难治性病例中手术是有效的。骨闪烁扫描被认为是对这些患者有用的检查方法,尽管我们不知道有大量系列研究支持这一点。34例有难治性髌腱炎症状的患者接受了手术治疗。对手术标本进行组织学分级,并与术前放射性核素骨扫描结果进行比较。组织学检查结果证实所有样本均存在肌腱和/或腱鞘异常。主要异常包括血管增多、成纤维细胞增殖、酸性粘多糖和含铁血黄素沉积。骨闪烁扫描显示24例(71%)患者延迟影像有异常,8例髌骨放射性活性弥漫性增加,16例放射性活性增加局限于下极。骨扫描异常的患者其肌腱组织学改变明显更严重。这些发现支持在髌腱炎术前评估中使用放射性核素骨扫描,其与疾病过程的组织病理学严重程度相关性良好。然而,10例假阴性病例(29%)表明骨扫描在这种疾病的常规诊断和治疗中并无帮助。

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