慢性闭塞性动脉疾病患者缺血肌肉组织中的氧分压
Oxygen pressure in ischemic muscle tissue of patients with chronic occlusive arterial diseases.
作者信息
Ehrly A M, Schroeder W
出版信息
Angiology. 1977 Feb;28(2):101-8. doi: 10.1177/000331977702800205.
Local tissue oxygen pressure was measured with micro-Pt-electrodes in the resting tibialis anterior muscles of 10 patients with chronic occlusive arterial disease and in 9 healthy subjects. The mean pO2 values in the patient group was 13.3 +/- 5.4 Torr, and 27.2 +/- 4.4 Torr in the control group. The difference is highly statistically significant. Preliminary results of treatment of 10 patients with the rheologically-active drug Ancrod show a statistically significant increase of oxygen pressure in the ischemic muscle tissue. Measurement of muscle tissue pO2 with microelectrodes seems to be an objective and quantitative method to investigate the oxygen supply to ischemic muscles and to judge the effects of therapeutic measures.
使用微型铂电极测量了10例慢性闭塞性动脉疾病患者和9名健康受试者静息状态下胫前肌的局部组织氧压。患者组的平均pO₂值为13.3±5.4托，对照组为27.2±4.4托。差异具有高度统计学意义。对10例患者使用流变活性药物安克洛进行治疗的初步结果显示，缺血肌肉组织中的氧压有统计学意义的升高。用微电极测量肌肉组织pO₂似乎是一种客观定量的方法，可用于研究缺血肌肉的氧供应情况并判断治疗措施的效果。
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