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[多发性硬化症的泌尿系统并发症。180例]

[Urologic complications of multiple sclerosis. 180 cases].

作者信息

Amarenco G, Bosc S, Boiteau F

机构信息

Service de Rééducation, Hôpital Robert Ballanger, Aulnay-sous-Bois.

出版信息

Presse Med. 1996 Jun 22;25(22):1007-10.

PMID:8692784
Abstract

OBJECTIVES

The aim of this study was to assess frequency and importance of urological complications in multiple sclerosis.

METHODS

A total of 180 patients with multiple sclerosis (115 women, 64 men; mean disease duration 13.4 years) underwent the following examinations: neuroperineal examination, bladder and kidney echography, intravenous pyelography, creatinine assay, urodynamic investigation and sphincter electromyography.

RESULTS

Detrusor hyperreflexia (70%) and areflexia (15%) were the commonest findings on cystometry and correlated with clinical data (urinary incontinence in 62% and retention in 18%). Urologic complications were noted in 56% with benign lesions in 37% (diverticula, urinary infections) and serious lesions in 19% (hydronephrosis, pyelonephritis, renal reflux). No correlations were found between complications and dyssynergia, overactivity and urinary retention.

CONCLUSIONS

The presence of these complications suggests the need for frequent urodynamic and radiologic controls in patients with multiple sclerosis.

摘要

目的

本研究旨在评估多发性硬化症患者泌尿系统并发症的发生率及重要性。

方法

总共180例多发性硬化症患者(115名女性,64名男性;平均病程13.4年)接受了以下检查:神经会阴检查、膀胱和肾脏超声检查、静脉肾盂造影、肌酐测定、尿动力学检查及括约肌肌电图检查。

结果

膀胱测压最常见的结果是逼尿肌反射亢进(70%)和无反射(15%),且与临床数据相关(62%有尿失禁,18%有尿潴留)。56%的患者存在泌尿系统并发症,其中37%为良性病变(憩室、泌尿系统感染),19%为严重病变(肾积水、肾盂肾炎、肾反流)。并发症与协同失调、活动亢进及尿潴留之间未发现相关性。

结论

这些并发症的存在表明,多发性硬化症患者需要频繁进行尿动力学和放射学检查。

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