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[足跟足底骨刺的放射治疗:适应症、技术、不同剂量概念下的临床结果]

[Radiotherapy of plantar heel spurs: indications, technique, clinical results at different dose concepts].

作者信息

Seegenschmiedt M H, Keilholz L, Stecken A, Katalinic A, Sauer R

机构信息

Strahlentherapeutische Klinik und Poliklinik, Universität Erlangen-Nürnberg.

出版信息

Strahlenther Onkol. 1996 Jul;172(7):376-83.

PMID:8693404
Abstract

BACKGROUND

In a retrospective study the efficacy of orthovoltage radiotherapy for refractory painful plantar heel spur was analyzed for 3 different radiation dose concepts.

PATIENTS AND METHODS

From 1.1 1984 through 1.3.1994, 182 patients with refractory painful heel symptoms and radiologically proven plantar heel spur received radiotherapy. A total of 141 patients and 170 heels (due to double-sided symptoms) were completely documented in long-term follow-up. Clearly defined semi-quantitative criteria (9-point score) were used to analyze heel pain and ankle function prior to RT, 6 to 12 weeks post-radiation, and at last follow-up. The treatment outcome, i.e. (un)favourable response, of 3 radiation dose concepts were compared: Group A (n = 72 heels) received 12 Gy total radiation dose in 3 fractions per week and 2 series (6 x 1 Gy per series) separated by 6 weeks; group B (n = 98 heels) received 3 Gy total radiation dose in 10 fractions of 0.3 Gy (n = 50) or 5 Gy (10 x 0.5 Gy) (n = 48) with conventional fractionation in 1 series.

RESULTS

Radiotherapy was very effective: at last follow-up 67% (group A) and 71% (group B) remained completely free of pain. The rate of "complete pain relief" (i.e. free of any pain symptoms) was not different between the 3 radiation concepts. However, significant differences were observed with regard to "incomplete or insufficient pain relief", i.e. a subjective pain relief of less than 80%, a delayed pain relief after more than 4 weeks or a relapse of pain symptoms in long-term follow-up. More favourable results were achieved in patients receiving 5 Gy or 12 Gy total dose, while patients with 3 Gy total dose had significantly worse results. Prognostic factors for "complete pain relief" were short duration of pain symptoms and acute pain symptoms prior to radiotherapy; with regard to "in-complete or insufficient pain relief" the total dose was found to be a prognostic parameter.

CONCLUSIONS

Patients with refractory heel pain can yield a high response to radiotherapy even after failing various conventional treatments previously. Thus, radiotherapy should not be solely regarded as a last resort due to its low costs and high efficacy at low radiation doses.

摘要

背景

在一项回顾性研究中,分析了3种不同放射剂量方案对顽固性疼痛性足底足跟骨刺进行正电压放射治疗的疗效。

患者与方法

从1984年1月1日至1994年3月1日,182例有顽固性足跟疼痛症状且经放射学证实有足底足跟骨刺的患者接受了放射治疗。共有141例患者和170只足跟(因双侧症状)被完整记录并进行长期随访。采用明确界定的半定量标准(9分制评分)分析放疗前、放疗后6至12周以及最后随访时的足跟疼痛和踝关节功能。比较了3种放射剂量方案的治疗结果,即(不)有利反应:A组(n = 72只足跟)每周分3次共接受12 Gy总放射剂量,分2个疗程(每个疗程6×1 Gy),疗程间隔6周;B组(n = 98只足跟)接受1个疗程的常规分割放疗,总放射剂量3 Gy,分10次,每次0.3 Gy(n = 50)或5 Gy(10×0.5 Gy)(n = 48)。

结果

放射治疗非常有效:在最后随访时,A组67%和B组71%的患者完全无痛。3种放射方案之间“完全缓解疼痛”(即无任何疼痛症状)的比例无差异。然而,在“不完全或不足的疼痛缓解”方面观察到显著差异,即主观疼痛缓解小于80%、4周后延迟疼痛缓解或长期随访中疼痛症状复发。接受5 Gy或12 Gy总剂量的患者取得了更有利的结果,而总剂量为3 Gy的患者结果明显较差。“完全缓解疼痛”的预后因素是疼痛症状持续时间短和放疗前有急性疼痛症状;对于“不完全或不足的疼痛缓解”,总剂量是一个预后参数。

结论

即使在先前各种常规治疗失败后,顽固性足跟疼痛患者对放射治疗仍可产生高反应。因此,由于放射治疗成本低且在低放射剂量下疗效高,不应仅将其视为最后手段。

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