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苏格兰东南部的肺癌管理

Management of lung cancer in South East Scotland.

作者信息

Fergusson R J, Gregor A, Dodds R, Kerr G

机构信息

Eastern General Hospital, Edinburgh, UK.

出版信息

Thorax. 1996 Jun;51(6):569-74. doi: 10.1136/thx.51.6.569.

Abstract

BACKGROUND

There are few reports which describe the management of unselected groups of patients with lung cancer. This study was undertaken to audit prospectively the presentation, diagnosis, management, and outcome of patients presenting with lung cancer in South East Scotland.

METHODS

Data were recorded on all patients with newly diagnosed lung cancer who presented to a multidisciplinary group of clinicians over a 12 month period. Subsequent follow up data on treatment and survival were collected.

RESULTS

Six hundred and twenty two patients were registered, 80% of whom were referred from primary care. There was a considerable variation in the length of history, but the diagnosis was rapidly made after referral (87% within two weeks). In 82% of patients the pathological examination was positive; 70% were treated with palliative intent. Only 36% of patients who underwent surgery had computed tomographic scanning and 55% had sampling of mediastinal nodes. A wide variety of regimens was used for treatment with radiotherapy and chemotherapy, and follow up data were difficult to obtain in these patients. Survival was poor in all patients treated with palliative intent.

CONCLUSIONS

This audit confirms the importance of previously noted prognostic factors. Significant variation in referral practice, diagnostic and management evaluation has been shown. The data serve as a useful background for the formation of local management guidelines.

摘要

背景

很少有报告描述对未经挑选的肺癌患者群体的管理。本研究旨在对苏格兰东南部肺癌患者的就诊情况、诊断、管理及预后进行前瞻性审核。

方法

记录了在12个月期间向多学科临床医生团队就诊的所有新诊断肺癌患者的数据。随后收集了关于治疗和生存的随访数据。

结果

登记了622例患者,其中80%是由初级医疗转诊而来。病史长度存在很大差异,但转诊后诊断迅速做出(87%在两周内)。82%的患者病理检查呈阳性;70%接受姑息性治疗。接受手术的患者中只有36%进行了计算机断层扫描,55%进行了纵隔淋巴结取样。放疗和化疗使用了多种方案,这些患者的随访数据难以获得。所有接受姑息性治疗的患者生存情况较差。

结论

本次审核证实了先前指出的预后因素的重要性。已显示出转诊实践、诊断和管理评估存在显著差异。这些数据为制定当地管理指南提供了有用的背景。

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