Jenkins M P, Alvaranga J C, Thomas J M
Soft Tissue Sarcoma Unit, Royal Marsden Hospital, London, U.K.
Eur J Cancer. 1996 Apr;32A(4):622-6. doi: 10.1016/0959-8049(95)00638-9.
Over a 5-year period, all retroperitoneal soft tissue sarcomas (119) referred to the Royal Marsden Hospital, London, U.K., were recorded prospectively on a database and managed with a consistent treatment policy. On multivariate analysis, the significant factors responsible for determining prognosis were grade and completeness of excision. Despite improvements in surgical clearance rates (nearly 50% completely excised in this series), the prognosis was poor with 2- and 5-year survival rates of 53 and 20%, respectively. Further improvements in survival rates will depend on better adjuvant treatment.
在5年期间，前瞻性地将转诊至英国伦敦皇家马斯登医院的所有腹膜后软组织肉瘤（119例）记录在数据库中，并采用一致的治疗策略进行管理。多因素分析显示，决定预后的重要因素是肿瘤分级和切除完整性。尽管手术切缘阳性率有所改善（本系列中近50%为完全切除），但预后仍然较差，2年和5年生存率分别为53%和20%。生存率的进一步提高将取决于更好的辅助治疗。
