Walker E M, Gale G R, Atkins L M, Gadsden R H
Arch Environ Contam Toxicol. 1977;5(3):333-41. doi: 10.1007/BF02220915.
The effects of dieldrin and mirex on Ehrlich ascites tumor cells were assessed, using certain in vivo (in mice) and in vitro measurements. Mirex retarded the development of Ehrlich ascites tumor in vivo, but dieldrin did not. Effects of dieldrin on de nova RNA purine synthesis from formate in vivo were slight, while mirex inhibited the synthesis of both RNA purines. Dieldrin inhibited the in vitro incorporation if thymidine, uridine, and L-leucine into DNA, RNA, and protein, respectively, but mirex was virtually without effect.
使用某些体内（在小鼠中）和体外测量方法，评估了狄氏剂和灭蚁灵对艾氏腹水癌细胞的影响。灭蚁灵在体内延缓了艾氏腹水瘤的发展，但狄氏剂没有。狄氏剂对体内由甲酸盐从头合成RNA嘌呤的影响轻微，而灭蚁灵抑制了两种RNA嘌呤的合成。狄氏剂分别在体外抑制了胸腺嘧啶核苷、尿苷和L-亮氨酸掺入DNA、RNA和蛋白质，但灭蚁灵实际上没有作用。
