Cryer P E
Arch Intern Med. 1977 Jun;137(6):783-7.
Patients with hypertension due to the release of large amounts of NE from a pheochromocytoma and patients with PAD and postural hypotension due to diminished NE release from adrenergic axon terminals represent the extremes of the spectrum of adrenergic pathophysiolgic findings. It is reasonable to suspect that some more common disorders lie between these extremes and to anticipate that potential roles of the adrenergic nervous system in the pathogenesis of these disorders will be extensively studied with the availability of sensitive isotope-derivative methods for the measurement of catecholamine levels in plasma and in tissue.
由于嗜铬细胞瘤释放大量去甲肾上腺素而导致高血压的患者，以及由于肾上腺素能轴突终末去甲肾上腺素释放减少而导致外周动脉疾病和体位性低血压的患者，代表了肾上腺素能病理生理结果谱的两个极端。有理由怀疑，在这些极端情况之间存在一些更常见的疾病，并预期随着用于测量血浆和组织中儿茶酚胺水平的灵敏同位素衍生方法的出现，肾上腺素能神经系统在这些疾病发病机制中的潜在作用将得到广泛研究。
