Storek J
Fred Hutschinson Cancer Research Center, University of Washington School of Medicine, Seattle, USA.
Cas Lek Cesk. 1996 May 15;135(10):295-8.
In the paper hepatic dysfunctions occurring in more than 80% recipients of HLA-matched bone marrow transplants (BMT) in the early post-transplant period (< 100 days) is described. They involve veno-occlusive disease (VOD) and acute graft-versus-host disease (aGVHD). Liver dysfunctions can be also caused by unfavourable effects of drugs and by infections. Etiopathogenesis, clinical and laboratory findings, diagnosis, therapy and prophylaxis of the dysfunctions in question is being described in detail.
本文描述了在移植后早期（<100天）接受 HLA 匹配骨髓移植（BMT）的80%以上受者中出现的肝脏功能障碍。这些功能障碍包括静脉闭塞性疾病（VOD）和急性移植物抗宿主病（aGVHD）。肝脏功能障碍也可能由药物的不良作用和感染引起。本文详细描述了上述功能障碍的病因发病机制、临床和实验室检查结果、诊断、治疗及预防。
