• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: an analysis of 618 individuals.

作者信息

Ko Y L, Hsu T S, Wu S M, Ko Y S, Chang C J, Wang S M, Chen W J, Cheng N J, Kuo C T, Chiang C W, Lee Y S

机构信息

Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.

出版信息

Hum Genet. 1996 Aug;98(2):176-7. doi: 10.1007/s004390050184.

DOI:10.1007/s004390050184
PMID:8698336
Abstract

To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese.

摘要

相似文献

1
The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: an analysis of 618 individuals.
Hum Genet. 1996 Aug;98(2):176-7. doi: 10.1007/s004390050184.
2
Venous thrombosis: factor V G1691A genotyping related to APC resistance as measured by 2 methods.静脉血栓形成：通过两种方法测量的与活化蛋白C抵抗相关的因子V G1691A基因分型
Eur J Haematol. 1997 Apr;58(4):229-32. doi: 10.1111/j.1600-0609.1997.tb01659.x.
3
Discrimination between normal wildtype and carriers of coagulation factor V Leiden mutation by the activated protein C resistance test in the presence of factor V deficient plasma.在缺乏因子V的血浆存在的情况下，通过活化蛋白C抵抗试验鉴别正常野生型与凝血因子V莱顿突变携带者。
Eur J Clin Chem Clin Biochem. 1997 Jan;35(1):41-5. doi: 10.1515/cclm.1997.35.1.41.
4
Ethnic distribution of factor V Leiden in 4047 men and women. Implications for venous thromboembolism screening.4047名男性和女性中凝血因子V莱顿突变的种族分布。对静脉血栓栓塞筛查的意义。
JAMA. 1997;277(16):1305-7.
5
Population study of the G1691A mutation (R506Q, FV Leiden) in the human factor V gene that is associated with resistance to activated protein C.
Hum Genet. 1996 Feb;97(2):263-4. doi: 10.1007/BF02265279.
6
Increased risk for venous thrombosis in carriers of the prothrombin G-->A20210 gene variant.凝血酶原G20210A基因变异携带者发生静脉血栓形成的风险增加。
Ann Intern Med. 1998 Jul 15;129(2):89-93. doi: 10.7326/0003-4819-129-2-199807150-00003.
7
The factor V Leiden mutation: spectrum of thrombotic events and laboratory evaluation.凝血因子V莱顿突变：血栓形成事件谱及实验室评估
J Vasc Surg. 1997 Feb;25(2):271-5; discussion 276. doi: 10.1016/s0741-5214(97)70348-3.
8
Age-specific incidence rates of venous thromboembolism among heterozygous carriers of factor V Leiden mutation.凝血因子V莱顿突变杂合子携带者中静脉血栓栓塞的年龄特异性发病率。
Ann Intern Med. 1997 Apr 1;126(7):528-31. doi: 10.7326/0003-4819-126-7-199704010-00005.
9
Factor V Leiden is not common in patients diagnosed with primary pulmonary hypertension.在被诊断为原发性肺动脉高压的患者中，凝血因子V莱顿突变并不常见。
Eur Respir J. 1998 Nov;12(5):1177-80. doi: 10.1183/09031936.98.12051177.
10
A case control study of deep venous thrombosis in relation to factor V G1691A (Leiden) and A4070G (HR2 Haplotype) polymorphisms.一项关于因子V G1691A（莱顿）和A4070G（HR2单倍型）多态性与深静脉血栓形成关系的病例对照研究。
Exp Mol Pathol. 2007 Dec;83(3):480-3. doi: 10.1016/j.yexmp.2007.04.006. Epub 2007 May 6.