Takeda S, Tatara I, Kono K, Arakawa K
Second Department of Internal Medicine, Fukuoka University School of Medicine, Japan.
Kansenshogaku Zasshi. 1996 May;70(5):437-40. doi: 10.11150/kansenshogakuzasshi1970.70.437.
Clinical efficacy of fluconazole on fungal infections was evaluated. Fluconazole was administrated orally or intravenously to 16 cases with fungal infections (chronic renal failure 4, congestive heart failure 2, cerebral infarction 2, etc). All cases were suspected of mycosis. The details of those administrated were 16 cases of pneumonia 3 cases, fungemia 9 cases (suspected 7 cases) and urinary tract infection 3 cases. Clinical efficacy rate was 71.4%. Side-effects were observed in only 1 case, and this consisted of transient increase of leukocytes and thrombocytes. Fluconazole is considered to be a potent, safe antifungal agent for the treatment of suspected fungal infection during intravenous hyperalimentation.
评估了氟康唑对真菌感染的临床疗效。对16例真菌感染患者（慢性肾衰竭4例、充血性心力衰竭2例、脑梗死2例等）口服或静脉给予氟康唑。所有病例均疑似霉菌感染。给药详情为肺炎3例、真菌血症9例（疑似7例）、尿路感染3例，共16例。临床有效率为71.4%。仅1例观察到副作用，表现为白细胞和血小板短暂升高。氟康唑被认为是一种强效、安全的抗真菌药物，可用于治疗静脉高营养期间的疑似真菌感染。
