[The role of free radicals in pathogenesis of insulin dependent diabetes mellitus].
作者信息
Komosińska K, Olczyk K
机构信息
Katedra i Zakład Chemii Klinicznej i Diagnostyki Laboratoryjnej Slaskiej Akademii Medycznej w Sosnowcu.
出版信息
Postepy Hig Med Dosw. 1995;49(6):733-46.
PMID:8700808
Abstract
The role of free radicals as well as cytokines (IL-1, tumor necrosis factor alpha, interferon gamma) and nitric oxide in the immune-mediated processes leading to the beta-cell destruction during IDDM is described. It is also pointed that the excess of IL-1ra in relation to IL-1 prevents IL-1 toxicity to beta-cells.
摘要
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