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以血小板减少为表现的系统性红斑狼疮。一名抗心磷脂抗体阳性儿童的病例报告。

Systemic lupus erythematosus presenting with thrombocytopenia. Report of a child with positive anticardiolipin antibodies.

作者信息

Kanra G, Erdem G, Ozen S, Anlar F Y, Beşbaş N, Ceyhan M

机构信息

Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara.

出版信息

Turk J Pediatr. 1996 Apr-Jun;38(2):231-4.

PMID:8701490
Abstract

We report a case of systemic lupus erythematosus initially presenting with thrombocytopenia and diagnosed as immune thrombocytopenic purpura. The patient subsequently developed lymphadenopathy, arthritis and cardiac involvement along with anticardiolipin antibodies. We would like to emphasize the fact that these autoantibodies have a role in the pathogenesis of thrombocyte destruction, and that patients with immune thrombocytopenic purpura should be followed for signs of systemic lupus erythematosus.

摘要

我们报告一例系统性红斑狼疮,最初表现为血小板减少症,被诊断为免疫性血小板减少性紫癜。该患者随后出现淋巴结病、关节炎和心脏受累,并伴有抗心磷脂抗体。我们想强调的是,这些自身抗体在血小板破坏的发病机制中起作用,并且免疫性血小板减少性紫癜患者应密切关注是否出现系统性红斑狼疮的迹象。

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