Esterre P, Andriantsimahavandy A, Ramarcel E R, Pecarrere J L
Parasitology Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar.
Am J Trop Med Hyg. 1996 Jul;55(1):45-7. doi: 10.4269/ajtmh.1996.55.45.
Confirmed cases of chromoblastomycosis in Madagascar from 1955 through 1994 were studied retrospectively. The total number of cases reported was 1,343, of which 98.5% were confirmed by histopathology. Only 30.8% of the cases showed a positive cultivation on mycologic media, and Fonsecaea pedrosoi was identified from 61.8% of the fungal strains. Two distinct areas of endemic chromoblastomycosis, each with a characteristic ecosystem and a single species, are identified. Madagascar represents the most important focus of this fungal disease described to date in the world.
对1955年至1994年马达加斯加确诊的着色芽生菌病病例进行了回顾性研究。报告的病例总数为1343例,其中98.5%经组织病理学确诊。只有30.8%的病例在真菌培养基上培养呈阳性,从61.8%的真菌菌株中鉴定出裴氏瓶霉。确定了两个不同的着色芽生菌病流行区,每个区都有独特的生态系统和单一菌种。马达加斯加是迄今为止世界上描述的这种真菌病最重要的疫源地。