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A 47-bp sequence of the first intron of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte Expression.

作者信息

Lefebvre V, Mukhopadhyay K, Zhou G, Garofalo S, Smith C, Eberspaecher H, Kimura J H, de Crombrugghe B

机构信息

Department of Molecular Genetics, University of Texas, M.D. Anderson Cancer Center, Houston 77030, USA.

出版信息

Ann N Y Acad Sci. 1996 Jun 8;785:284-7. doi: 10.1111/j.1749-6632.1996.tb56285.x.

DOI:10.1111/j.1749-6632.1996.tb56285.x
PMID:8702156
Abstract
摘要

相似文献

1
A 47-bp sequence of the first intron of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte Expression.
Ann N Y Acad Sci. 1996 Jun 8;785:284-7. doi: 10.1111/j.1749-6632.1996.tb56285.x.
2
Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene.利用一种新的大鼠软骨肉瘤细胞系来描绘一个119个碱基对的软骨细胞特异性增强子元件，并确定小鼠原α1（II）型胶原基因中的活性启动子片段。
J Biol Chem. 1995 Nov 17;270(46):27711-9. doi: 10.1074/jbc.270.46.27711.
3
A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice.小鼠原α1（II）型胶原蛋白基因的一个182bp片段足以在转基因小鼠中指导软骨细胞表达。
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4
Characterization of type II and type XI collagen synthesis by an immortalized rat chondrocyte cell line (IRC) having a low level of type II collagen mRNA expression.具有低水平II型胶原mRNA表达的永生化大鼠软骨细胞系（IRC）对II型和XI型胶原合成的特征分析
Exp Cell Res. 1994 Jul;213(1):28-36. doi: 10.1006/excr.1994.1169.
5
The transcriptional tissue specificity of the human pro alpha 1 (I) collagen gene is determined by a negative cis-regulatory element in the promoter.人类原α1（I）型胶原基因的转录组织特异性由启动子中的一个负性顺式调控元件决定。
Biochem J. 1992 Aug 15;286 ( Pt 1)(Pt 1):179-85. doi: 10.1042/bj2860179.
6
Separable regulatory elements from pro-alpha 2 (XI) collagen gene drive distinct patterns of cartilage-specific expression in transgenic mice.
Ann N Y Acad Sci. 1996 Jun 8;785:340-2. doi: 10.1111/j.1749-6632.1996.tb56303.x.
7
Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts.鉴定小鼠原α1（I）型胶原启动子的最小序列，该序列在转基因小鼠中赋予高水平的成骨细胞表达，并与成骨细胞中选择性存在的一种蛋白质结合。
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1027-31. doi: 10.1073/pnas.93.3.1027.
8
High levels of expression of a minigene version of the human pro alpha 1 (I) collagen gene in stably transfected mouse fibroblasts. Effects of deleting putative regulatory sequences in the first intron.
J Biol Chem. 1991 Jan 15;266(2):1117-21.
9
Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse.II型前胶原基因调控元件的结构分析。人和小鼠之间启动子和第一内含子序列的保守性。
Biochem J. 1992 Jul 1;285 ( Pt 1)(Pt 1):287-94. doi: 10.1042/bj2850287.
10
DNA sequences in the first intron of the human pro-alpha 1(I) collagen gene enhance transcription.
J Biol Chem. 1987 Nov 5;262(31):15151-7.

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