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妥复芬联合治疗慢性循环衰竭患者的临床疗效

[The clinical efficacy of taufon in the combined treatment of patients with chronic circulatory failure].

作者信息

Zavolovskaia L I, Elizarova E P, Orlov V A

出版信息

Eksp Klin Farmakol. 1995 Nov-Dec;58(6):29-32.

PMID:8704607
Abstract

Monotherapeutic treatment of patients with chronic cardiac insufficiency of I and II functional class and patients of III FC with Russian drug taufon against the background of traditional therapy leads to improvement of objective and subjective indications of the disease. Taufon does not significantly affect central hemodynamics, but normalizes contractile myocardial function and increases tolerance to physical load. Taufon potentiates therapeutic efficacy of some drugs that makes it possible to reduce their doses. Pharmacokinetics is given. The efficacy and the absence of any toxic effects allow the authors to recommend the drug for treatment of patients with chronic cardiovascular as an drug additional to basic background therapy.

摘要

对I级和II级心功能不全患者以及III级心功能不全患者在传统治疗基础上加用俄罗斯药物taufor进行单药治疗,可改善疾病的客观和主观指标。taufor对中心血流动力学无显著影响,但可使心肌收缩功能正常化并提高对体力负荷的耐受性。taufor可增强某些药物的治疗效果,从而有可能降低其剂量。文中给出了药代动力学情况。其疗效及无任何毒性作用使作者推荐该药物作为基础背景治疗之外的药物用于慢性心血管疾病患者的治疗。

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