自体红细胞回收与骨髓移植后多发性骨髓瘤的复发：这是移植物抗骨髓瘤效应吗？
Autologous red cell recovery and relapse of multiple myeloma after bone marrow transplantation: is this a graft-versus-myeloma effect?
作者信息
Forsyth C, Nelson M, Popp H, Snowdon L, Gibson J, Joshua D
机构信息
Institute of Haematology, Royal Prince Alfred Hospital, Camperdown, Australia.
出版信息
Bone Marrow Transplant. 1996 Mar;17(3):457-9.
PMID:8704707
Abstract
We report a patient who, following an allogeneic bone marrow transplant for multiple myeloma, recovered autologous erythropoiesis which was rapidly followed by relapse of her multiple myeloma. We postulate that the loss of the graft (as demonstrated by loss of donor erythropoiesis) and subsequent relapse of the multiple myeloma may be support for the existence of a graft-versus-myeloma effect.
摘要
我们报告了一名患者，她在接受异基因骨髓移植治疗多发性骨髓瘤后，自体红细胞生成得以恢复，但随后多发性骨髓瘤迅速复发。我们推测，移植物的丧失（如供体红细胞生成的丧失所示）以及随后多发性骨髓瘤的复发可能支持移植物抗骨髓瘤效应的存在。
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